The genus Sonerila is a member of the tribe Sonerileae of the family Melastomataceae, with about ca. 175 species in tropical and subtropical areas from India to Papua New Guinea. The flowers of Sonerila are bisexual, 3-merous and born on scorpioid inflorescence, and Sonerila is clearly distinguished from other genus in Melastomataceae by them. For the Indochinese Peninsula, 4 species have been reported from Cambodia, 7 from Laos, 15 from Thailand, and 8 from Vietnam. From 2015, we have participated in SE Asian Countries’s Biodiversity Survey Project conducted by National Institute of Biological Resources, Korea and have chance to collect Sonerila species from Laos. Here we are reporting two new Sonerila species, S. kaysonia K.E. Lee & H. Won and S. bolikhamxaiana K.E. Lee & H. Won. Sonerila kaysonia sp. nov. is epiphytic on rocks and characterized drooping and horizontally spreading habit, with the largest flower of all the Sonerila taxa so far reported from Lao PDR. Sonerila bolikhamxaiana is erect on ground and has glandular hairs on the petal and on the adaxial mid-vein of leaves.